CAS 490-46-0 L-Epicatechin
Description (−)-Epicatechin is a polyketide synthase-derived polyphenol flavonoid that has been found in T. cacao and has diverse biological activities. It scavenges DPPH radicals in a cell-free assay when used at a concentration of 5 μM. (−)-Epicatechin inhibits COX-1 (IC50 = 3.2 μM). It acts synergistically with epigallocatechin gallate to induce apoptosis in, and reduce the proliferation of, PC-9 lung cancer cells when used at a concentration of 200 μM. (−)-Epicatechin (80 mg/kg) reduces LPS-induced increases in plasma creatinine and urea levels in a rat model of renal inflammation.
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Product Name: L-Epicatechin
Synonyms: 3,3',4',5,7-PENTAHYDROXY-FLAVANE;3,3',4',5,7-PENTAHYROXYFLAVONE;3,3',4',5,7-PENTAHYDROXYFLAVAN;(2R,3R)-2-(3,4-DIHYDROXYPHENYL)-3,4-DIHYDRO-1(2H)-BENZOPYRAN-3,5,7-TRIOL;(-)-epicatecho;(-)-epicatechol;(-)-EPICATECHIN;(+)-EPICATECHIN
CAS: 490-46-0
MF: C15H14O6
MW: 290.27
EINECS: 207-710-1
Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Pharmaceutical Raw Materials;Aromatics;Chiral Reagents;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;chiral;490-46-0
form Solid
pka 9.54±0.10(Predicted)
color White to Light yellow to Light orange
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